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An independent charity, working to improve the prevention and management of obesity.
Research Reports
see also NOF in the Media for media coverage of research projects quoting NOF reaction 


NOF Reaction to `Weighing Up the Burden of Obesity’ report
By Dr Colin Waine, Chair of the NOF
 
THE National Obesity Forum welcomes the publication of the new report by Dr Foster Research, `Weighing Up the Burden of Obesity’ (http://www.drfosterintelligence.co.uk/newsPublications/localDocuments/WeighingUpTheBurdenOfObesityReport.pdf).
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New studies provide conflicting evidence on mortality and intensive diabetes treatment
By Rhonda Siddall

28th February, 2008

INTERIM results from the ADVANCE Study, involving 11,140 high-risk patients with Type 2 diabetes provide no evidence of an increased risk of death among those patients receiving intensive treatment to lower blood glucose.

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Higher body mass index means higher risk of several cancers
 
By Rhonda Siddall
15th February 2008

 
Genehan AG, Tyson M, Egger M, et al. BMI and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. The Lancet 371:569-578

INCREASED body mass index (BMI) increases the risk of common and less common cancers, new research has confirmed.
 
A paper published in this week’s Lancet also showed that the level of risk can vary between the sexes and different ethnic groups depending on the type of cancer.
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“Evidence for strong genetic influence on childhood adiposity despite the force of the obesogenic en
Jane Wardle et al
 
The N.O.F. welcomes the paper by Professor Jane Wardle and colleagues and considers it to be an important contribution to our understanding of the many issues contributing to the present epidemic of obesity which so threatens the future wellbeing of so many children.
 
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“ It's his genes, doc! “
February 7th 2008 
 
Doctors all over the world will be familiar with the above line when facing parents of overweight boys – or girls for that matter – unwilling to consider that overindulgence has anything to do with their fatness.  It appears, however, that they may have a point..  To-day’s publication of “ Evidence for strong genetic influence on childhood adiposity despite the force of the obesogenic environment “ [Wardle J, Carnell S, Haworth C & Plomin R, American Journal of Clinical Nutrition] confirms the argument.  Wardle’s paper indicates that the adiposity in pre-adolescent children born since the onset of the obesity epidemic is highly heritable and that differences in body mass index [BMI] and waist size may be 77% governed by genes.
 
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NOF Statement - Anti-Obesity Medication
16th November 2007
 
The National Obesity Forum (NOF) remains convinced that the use of anti-obesity medication, in line with NICE guidance, is justified in serious medical condition.
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Long term pharmacotherapy for obesity and overweight
Rhonda Siddall [NOF Special Correspondent] 16th November 2007

Patients taking anti-obesity drugs will see only modest weight loss and many will remain significantly obese or overweight, according to a study published in the British Medical Journal. But the National Obesity Forum (NOF) remains convinced that the use of anti-obesity medication is clinically justified (see full statement NOF reaction to BMJ anti-obesity drugs study).

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Government and industry not doing enough for our health
13th November 2007
 
The Government and industry are not doing enough to help people live healthy lives, says the Nuffield Council on Bioethics in a report on public health ethics published today. The report, which highlights the importance of reducing health inequalities, looks specifically at alcohol, obesity, smoking, infectious disease and fluoridation of water.
 
“People often reject the idea of a ‘nanny state’,” said Lord Krebs, who chaired the committee that produced the report. “But the Government has a duty to look after the health of everyone and sometimes that means guiding or restricting our choices.” 
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New test could measure levels of dangerous fat stored around organs
Rhonda Siddall [NOF Special Correspondent] 05 November 2007
 
NEW research presented at the recent European Association for the Study of Diabetes (EASD) suggests that measuring levels of a protein in the blood could provide an accurate way to assess how much `dangerous’ fat is stored around the body’s vital organs.
 
The build-up of this so-called visceral fat has been linked to an increased risk of heart disease and type 2 diabetes and is more dangerous to health than fat that is deposited under the skin rather than in and around tissues and organs such as muscle and the liver. Visceral fat is metabolically more active than subcutaneous fat and can trigger reactions in the body that disturb metabolic processes.
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Excess Body Fat Causes a Range of Cancers
Rhonda Siddall [NOF special correspondent]  01 November 2007

A landmark report has recommended that everyone should aim to be as lean as possible within the healthy weight range to cut their risk of at least six cancers including breast, bowel and pancreatic cancer.  

Identifying weight as a key factor in many cancers, the World Cancer Research Fund (WCRF) report said that convincing evidence exists that excess body fat is the main culprit in many common cancers. The report is the largest review of links between diet and cancer, based on more than 7,000 studies. Ten years ago, when the WCRF published its previous report on diet and cancer, this review said the evidence showed obesity and overweight were implicated in only one type of cancer (cancer of the womb lining). But the report’s authors say that the evidence that has accumulated over the past decade now shows that excess body fat is a significant risk factor for a range of cancers. Professor Sir Michael Marmot, chair of the expert panel that interpreted the evidence, said that even modest weight gains were associated with cancer risk. He told a press conference at the Royal Society yesterday: “The healthiest thing is to be as low as possible within the normal range.”  

 
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Promoting physical activity in adolescents requires multilevel approach
BMJ 2007 doi: 10.1136/bmj.39320.843947.BE By Rhonda Siddall [Colin Waine]
 
A NEW review of the published literature on interventions to promote physical activity in children and adolescents found more evidence of an effect among adolescents than among children.
 
Published in this week’s BMJ, the review found weak or inconclusive evidence for the effectiveness of strategies to promote children's physical activity.
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"Fat Eggs" Likely Cause of Infertility in Obese Women
University of Adelaide  23 August 2007
 
A researcher at the University of Adelaide, Australia, has discovered scientific evidence that obesity is a key factor in infertility – because of how it affects women's eggs.  While obesity has long been thought to be a major factor in couples' inability to conceive, this is the first time the effects of obesity on the egg have been discovered.  The research findings – using female mice – have been made by PhD student Cadence Minge in the University of Adelaide's Research Centre for Reproductive Health. 
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What Doctors Don't Say About Obesity
Mayo Clinic Proceedings  August 2007
 
If there's one place where it's a good idea to come clean, it's the doctor's office. Patients with an ache, a symptom or a bad habit like smoking do no one any good if they keep it to themselves. Yet there's one time doctors are often less than forthcoming: when they have to tell patients they need to lose weight.
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Heavy kids miss more school days
Obesity August 2007
 
A new study suggests that overweight children tend to miss more days of school than their normal-weight peers -- a fact, researchers say, that could put them at an academic disadvantage.   In a study of more than 1,000 students attending Philadelphia elementary schools, researchers found that overweight children missed an average of 2 extra days out of the school year compared with normal-weight students.
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Parental Stress Can Keep Kids Obese
Obesity  August 2007

Parental stress or bullying by peers can make it even tougher for overweight or obese children to get healthy, a U.S. study finds.  "If a parent is distressed, that seems to impact a child's symptoms of depression, which then impacts quality of life. It's the same with peer victimization. It impacts depression, which then impacts quality of life. And it seems to affect not just the emotional aspect of quality of life, but also their health status," lead author David Janicke, assistant professor of clinical and health psychology in the University of Florida College of Public Health and Health Professions, in Gainesville, said in a prepared statement.
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Obese children 'suffering high blood pressure'
Daily Telegraph  22 August 2007

The obesity epidemic is causing an increase in the number of children with high blood pressure, doctors have warned.  New research has shown that the problems with obesity is causing conditions previously only seen in adults to be diagnosed in children.  Scientists who studied 14,187 children aged between three and 18 found that more than three per cent had high blood pressure but three quarters of them had not been properly diagnosed.  The team warned that doctors need to be more aware of the condition.
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Benefits of weight-loss surgery
International Herald Tribune 22 August 2007

The first long-term studies of stomach stapling and other radical obesity treatments show that they not only lead to lasting weight loss but also dramatically improve survival. The results are expected to lead to more such operations, possibly for less severely obese people, too.  Researchers in Sweden and the United States separately found that obese people who underwent drastic surgery had a 30 percent to 40 percent lower risk of dying seven to 10 years later compared with those who did not have such operations.
 
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Obese men at more risk of deadly form of prostate disease
The Guardian  20 August 2007
 
Obese men have a greater risk of developing one of the most aggressive and life-threatening forms of prostate cancer, scientists warn yesterday.   Researchers in Sweden found that while obese men have an overall lower risk of getting prostate cancer, those who do are more likely to develop a severe form of the disease that quickly spreads around the body and is more likely to kill them.  The finding emerged from a study of 784 men, half of whom were being treated for prostate cancer.  Those who were insulin-resistant, a condition closely linked to obesity, were at greatest risk of aggressive prostate cancer, the scientists said.
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Mothers-to-be child obesity warning
Guardian 15 August 2007 
 
Pregnant mothers-to-be who “ eat for two” by upping their intake of fatty and sugary food could unwittingly be putting their children at risk of obesity, new research suggests. The same applies to mothers who are breastfeeding, scientists have warned. Unborn babies and developing infants can have their eating habits programmed by their mothers’ food choices, according to the findings. Children exposed to “ maternal junk food “ in the womb or early in life may find it harder to resist an unhealthy diet as they grow older, say the researchers.
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Similar body fat a key attraction in potential mates
Independednt 08 August 2007
 
Humans choose partners with a similar body fat level to their own, according to research published yesterday.  For years scientists have known people tend to marry within their own social and educational class and race. But a study has now found people with roughly the same amount of body fat are likely to be attracted to each other.  Researchers also found this predisposition - called "assortive mating" - could be contributing to the world's obesity epidemic.  This is because children who have an overweight mother and father get a double dose of the genes that make them susceptible to piling on the pounds
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Children of obese mums ‘more likely to have birth defects'
Daily Mail  07 Aug 2007

Obese women are more at risk of having babies with birth defects, say researchers. At least seven types of health problem are more likely to occur if a woman is grossly overweight when she becomes pregnant. The risk of spina bifida is doubled. Other conditions including heart and limb defects and hernia in the diaphragm are between 33 per cent and 63 per cent more prevalent in fat mothers.
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